Current Preprints
- Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow. René Riedel, Richard Kwasi Addo, Marta Ferreira-Gomes, Gitta Anne Heinz, Frederik Heinrich, Jannis Kummer, Victor Greiff, Daniel Schulz, Cora Klaeden, Rebecca Cornelis, Ulrike Menzel, Stefan Kröger, Ulrik Stervbo, Ralf Köhler, Claudia Haftmann, Silvia Kühnel, Katrin Lehmann, Patrick Maschmeyer, Mairi McGrath, Sandra Naundorf, Özen Sercan Alp, Stefanie Hahne, Francesco Siracusa, Jonathan Stefanowski, Melanie Weber, Kerstin Westendorf, Jakob Zimmermann, Anja E Hauser, Sai T Reddy, Pawel Durek, Hyun-Dong Chang, Mir-Farzin Mashreghi, Andreas Radbruch. bioRxiv
- A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding. Rahmad Akbar, Jeliazko R. Jeliazkov, Philippe A. Robert, Igor Snapkov, Milena Pavlović, Andrei Slabodkin, Cédric R. Weber, Lonneke Scheffer, , , , Yana Safonova, Geir K. Sandve, and Victor Greiff#. bioRxiv
- Mouse-specific but infection-unspecific IgM repertoire fingerprint following viral infection. Alexander Yermanos, Nike Julia Krautler, Alessandro Pedrioli, Ulrike Menzel, Victor Greiff, Tanja Stadler, Annette Oxenius, Sai T. Reddy. bioRxiv
- The influence of the phylogenetic inference pipeline on murine antibody repertoire sequencing data following viral infection. Alexander Yermanos, Victor Greiff, Tanja Stadler, Annette Oxenius, Sai T Reddy. bioRxiv
2020
- immuneSIM: tunable multi-feature simulation of B- and T-cell receptor repertoires for immunoinformatics benchmarking. Cédric R. Weber, Rahmad Akbar, Alexander Yermanos, Milena Pavlović, Igor Snapkov, Geir K. Sandve, Sai T. Reddy#, Victor Greiff#. Bioinformatics
- Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses. Bénédict Fallet, Yi Hao, Marianna Florova , Karen Cornille, Alba Verge de los Aires, Giulia Girelli Zubani, Yusuf I. Ertuna, Victor Greiff, Ulrike Menzel, Karim Hammad, Doron Merkler, Sai T. Reddy, Jean-Claude Weill, Claude-Agnès Reynaud, Daniel D. Pinschewer. Cell Reports.
- Quantitative and Qualitative Analysis of Humoral Immunity Reveals Continued and Personalized Evolution in Chronic Viral Infection. Nike Julia Kräutler, Alexander Yermanos, Alessandro Pedrioli, Suzanne P.M. Welten, Dominique Lorgé, Ute Greczmiel, Ilka Bartsch, Jörg Scheuermann, Jonathan D. Kiefer, Klaus Eyer, Ulrike Menzel, Victor Greiff, Dario Neri, Tanja Stadler, Sai T. Reddy, Annette Oxenius. Cell Reports.
2019
- Benchmarking immunoinformatic tools for the analysis of antibody repertoire sequences. Erand Smakaj, Lmar Babrak, Mats Ohlin, Mikhail Shugay, Bryan Briney, Deniz Tosoni, Christopher Galli, Vendi Grobelsek, Igor D’Angelo, Branden Olson, Sai Reddy, Victor Greiff, Johannes Trück, Susanna Marquez, William Lees, Enkelejda Miho. Bioinformatics.
- Augmenting adaptive immunity: progress and challenges in the quantitative engineering and analysis of adaptive immune receptor repertoires. Alex J. Brown, Igor Snapkov, Rahmad Akbar, Milena Pavlović, Enkelejda Miho, Geir K. Sandve#, Victor Greiff#. Molecular Systems Design and Engineering.
- Resident memory CD8 T cells persist for years in human small intestine. Raquel Bartolome Casado, Ole J. B. Landsverk, Sudhir Kumar Chauhan, Lisa Richter, Danh Phung, Victor Greiff, Louise Fremgaard Risnes, Ying Yao, Ralf Stefan Neumann, Sheraz Yaqub, Ole Øyen, Rune Horneland, Einar Martin Aandahl, Vemund Paulsen, Ludvig M. Sollid, Shuo-Wang Qiao, Espen S. Baekkevold, Frode L. Jahnsen. Journal of Experimental Medicine.
- Persistence of intrathecal oligoclonal B cells and IgG in multiple sclerosis. Alina Tomescu-Baciua, Jorunn N. Johansena, Trygve Holmøy, Victor Greiff, Maria Stensland, Gustavo Antonio de Souzaa, Frode Vartdal, Andreas Lossius. Journal of Neuroimmunology.
- Large-scale network analysis reveals the sequence space architecture of antibody repertoires. Enkelejda Miho, Rok Roškar, Victor Greiff# & Sai T. Reddy#. Nature Communications.
- Inferred allelic variants of immunoglobulin receptor genes: a system for their evaluation, documentation and naming. Mats Ohlin, Cathrine Scheepers, Martin Corcoran, William D. Lees, Christian E. Busse, Davide Bagnara, Linnea Thörnqvist, Jean-Philippe Bürckert, Katherine J. Jackson, Duncan K. Ralph, Chaim A. Schramm, Nishanth Marthandan, Felix Breden, Jamie K. Scott, Frederick A. Matsen IV, Victor Greiff, Gur Yaari, Steven H. Kleinstein, Scott Christley, Jacob S. Sherkow, Sofia Kossida, Marie-Paule Lefranc, Menno C. van Zelm, Corey T. Watson and Andrew M. Collins. Frontiers in Immunology.
2018
- High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis. Derek M Mason, Cédric R Weber, Cristina Parola, Simon M Meng, Victor Greiff, William J Kelton, Sai T Reddy. Nucleic Acids Research
- Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires. Enkelejda Miho , Alexander Yermanos, Cédric R. Weber, Christoph T. Berger, Sai T. Reddy#, Victor Greiff#. Frontiers in Immunology
2017
- Learning the High-Dimensional Immunogenomic Features that Predict Public and Private Antibody Repertoires. Victor Greiff*, Cédric R*. Weber, Johannes Palme, Ulrich Bodenhofer, Enkelejda Miho, Ulrike Menzel, Sai T Reddy. The Journal of Immunology
- Systems Analysis Reveals High Genetic and Antigen-Driven Predetermination of Antibody Repertoires throughout B Cell Development. Victor Greiff*, Ulrike Menzel*, Enkelejda Miho, Cédric Weber, René Riedel, Skylar Cook, Atijeh Valai, Telma Lopes, Andreas Radbruch, Thomas Winkler, Sai T Reddy. Cell Reports
- Comparison of methods for phylogenetic B-cell lineage inference using time-resolved antibody repertoire simulations (AbSim). Alexander Yermanos, Victor Greiff, Nike J Krautler, Ulrike Menzel, Andreas Dounas, Enkelejda Miho, Annette Oxenius, Tanja Stadler, Sai T Reddy. Bioinformatics
- Low immunoglobulin E flags two distinct types of immune dysregulation. Marius Elkuch,* Victor Greiff*, Christoph T Berger, M Bouchenaki, Thomas Daikeler, Andreas Bircher, Alexander A Navarini, Ingmar Heijnen, Mike Recher. Clinical and Experimental Immunology
- Adaptive Immune Receptor Repertoire Community recommendations for sharing immune-repertoire sequencing data. Florian Rubelt, Christian E Busse, Syed Ahmad Chan Bukhari, Jean-Philippe Bürckert, Encarnita Mariotti-Ferrandiz, Lindsay G Cowell, Corey T Watson, Nishanth Marthandan, William J Faison, Uri Hershberg, Uri Laserson, Brian D Corrie, Mark M Davis, Bjoern Peters, Marie-Paule Lefranc, Jamie K Scott, Felix Breden, The AIRR Community, Eline T Luning Prak, Steven H Kleinstein, Nature Immunology.
2015
- A bioinformatic framework for immune repertoire diversity profiling enables detection of immunological status. A bioinformatic framework for immune repertoire diversity profiling enables detection of immunological status. Victor Greiff, Pooja Bhat, Skylar C Cook, Ulrike Menzel, Wenjing Kang, Sai T Reddy. Genome Medicine
- Bioinformatic and statistical analysis of adaptive immune repertoires. Victor Greiff, Enkelejda Miho, Ulrike Menzel, Sai T Reddy. Trends in Immunology
- Influenza vaccine response profiles are affected by vaccine preparation and preexisting immunity, but not HIV infection. Christoph T Berger*, Victor Greiff*, Matthias Mehling, Stefanie Fritz, Marc A Meier, Gideon Hoenger, Anna Conen, Mike Recher, Manuel Battegay, Sai T Reddy, Christoph Hess, Human Vaccines & Immunotherapeutics
- Risk factors for pneumocystis pneumonia in giant cell arteritis: a single-centre cohort study. Christoph T Berger, Victor Greiff, S John, KF Koenig, Marc B Bigler, Mike Recher, Christoph Hess, Thomas Daikeler. Clinical and Experimental Rheumatology
2014
- Quantitative assessment of the robustness of next-generation sequencing of antibody variable gene repertoires from immunized mice. Victor Greiff*, Ulrike Menzel*, Ulrike Haessler, Skylar C Cook, Simon Friedensohn, Tarik A Khan, Mark Pogson, Ina Hellmann, Sai T Reddy. BMC Immunology
- Comprehensive evaluation and optimization of amplicon library preparation methods for high-throughput antibody sequencing. Ulrike Menzel*, Victor Greiff*, Tarik Khan, Ulrike Haessler, Ina Hellmann, Simon Friedensohn, Skyler C Cook, Mark Pogson, Sai T Reddy. PLoS One
2012
